An overview of recent developments in FLUKA PET tools.
Identifieur interne : 000478 ( Main/Exploration ); précédent : 000477; suivant : 000479An overview of recent developments in FLUKA PET tools.
Auteurs : R S Augusto [Allemagne] ; J. Bauer [Allemagne] ; O. Bouhali [Qatar] ; C. Cuccagna [Suisse] ; C. Gianoli [Allemagne] ; W S Kozłowska [Autriche] ; P G Ortega [Espagne] ; T. Tessonnier [France] ; Y. Toufique [Maroc] ; V. Vlachoudis [Suisse] ; K. Parodi [Allemagne] ; A. Ferrari [Suisse]Source :
- Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) [ 1724-191X ] ; 2018.
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Abstract
The new developments of the FLUKA Positron-Emission-Tomography (PET) tools are detailed. FLUKA is a fully integrated Monte Carlo (MC) particle transport code, used for an extended range of applications, including Medical Physics. Recently, it provided the medical community with dedicated simulation tools for clinical applications, including the PET simulation package. PET is a well-established imaging technique in nuclear medicine, and a promising method for clinical in vivo treatment verification in hadrontherapy. The application of clinically established PET scanners to new irradiation environments such as hadrontherapy requires further experimental and theoretical research to which MC simulations could be applied. The FLUKA PET tools, besides featuring PET scanner models in its library, allow the configuration of new PET prototypes via the FLUKA Graphical User Interface (GUI) Flair. Both the beam time structure and scan time can be specified by the user, reproducing PET acquisitions in time, in a particle therapy scenario. Furthermore, different scoring routines allow the analysis of single and coincident events, and identification of parent isotopes generating annihilation events. Two reconstruction codes are currently supported: the Filtered Back-Projection (FBP) and Maximum-Likelihood Expectation Maximization (MLEM), the latter embedded in the tools. Compatibility with other reconstruction frameworks is also possible. The FLUKA PET tools package has been successfully tested for different detectors and scenarios, including conventional functional PET applications and in beam PET, either using radioactive sources, or simulating hadron beam irradiations. The results obtained so far confirm the FLUKA PET tools suitability to perform PET simulations in R&D environment.
DOI: 10.1016/j.ejmp.2018.06.636
PubMed: 30017561
Affiliations:
- Allemagne, Autriche, Espagne, France, Maroc, Qatar, Suisse
- Basse-Normandie, Bavière, Canton de Genève, Castille-et-León, District de Haute-Bavière, Région Normandie, Vienne (Autriche)
- Caen, Garching bei München, Genève, Vienne (Autriche)
- Université Louis-et-Maximilien de Munich, Université de Genève
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Le document en format XML
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Electronic address: r.s.augusto@cern.ch.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland; Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Garching bei München</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Bauer, J" sort="Bauer, J" uniqKey="Bauer J" first="J" last="Bauer">J. Bauer</name><affiliation wicri:level="1"><nlm:affiliation>UniversitätsKlinikum Heidelberg, Heidelberger Ionenstrahl-Therapiezentrum HIT, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>UniversitätsKlinikum Heidelberg, Heidelberger Ionenstrahl-Therapiezentrum HIT</wicri:regionArea><wicri:noRegion>Heidelberger Ionenstrahl-Therapiezentrum HIT</wicri:noRegion><wicri:noRegion>Heidelberger Ionenstrahl-Therapiezentrum HIT</wicri:noRegion><wicri:noRegion>Heidelberger Ionenstrahl-Therapiezentrum HIT</wicri:noRegion></affiliation></author><author><name sortKey="Bouhali, O" sort="Bouhali, O" uniqKey="Bouhali O" first="O" last="Bouhali">O. Bouhali</name><affiliation wicri:level="1"><nlm:affiliation>Texas A&M University at Qatar, 23874 Doha, Qatar.</nlm:affiliation><country xml:lang="fr">Qatar</country><wicri:regionArea>Texas A&M University at Qatar, 23874 Doha</wicri:regionArea><wicri:noRegion>23874 Doha</wicri:noRegion></affiliation></author><author><name sortKey="Cuccagna, C" sort="Cuccagna, C" uniqKey="Cuccagna C" first="C" last="Cuccagna">C. Cuccagna</name><affiliation wicri:level="4"><nlm:affiliation>CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland; TERA Foundation, Via Puccini 11, 28100 Novara, Italy; Université de Genève, 30 quai Ernest-Ansermet, CH-1211 Genève, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland; TERA Foundation, Via Puccini 11, 28100 Novara, Italy; Université de Genève, 30 quai Ernest-Ansermet, CH-1211 Genève</wicri:regionArea><orgName type="university">Université de Genève</orgName><placeName><settlement type="city">Genève</settlement><region nuts="3" type="region">Canton de Genève</region></placeName></affiliation></author><author><name sortKey="Gianoli, C" sort="Gianoli, C" uniqKey="Gianoli C" first="C" last="Gianoli">C. Gianoli</name><affiliation wicri:level="4"><nlm:affiliation>Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Garching bei München</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Kozlowska, W S" sort="Kozlowska, W S" uniqKey="Kozlowska W" first="W S" last="Kozłowska">W S Kozłowska</name><affiliation wicri:level="3"><nlm:affiliation>CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland; Medizinische Universität Wien, Spitalgasse 23, 1090 Vienna, Austria.</nlm:affiliation><country xml:lang="fr">Autriche</country><wicri:regionArea>CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland; Medizinische Universität Wien, Spitalgasse 23, 1090 Vienna</wicri:regionArea><placeName><region type="land" nuts="2">Vienne (Autriche)</region><settlement type="city">Vienne (Autriche)</settlement></placeName></affiliation></author><author><name sortKey="Ortega, P G" sort="Ortega, P G" uniqKey="Ortega P" first="P G" last="Ortega">P G Ortega</name><affiliation wicri:level="2"><nlm:affiliation>Grupo de Física Nuclear, Universidad de Salamanca, E-37008 Salamanca, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Grupo de Física Nuclear, Universidad de Salamanca, E-37008 Salamanca</wicri:regionArea><placeName><region nuts="2" type="communauté">Castille-et-León</region></placeName></affiliation></author><author><name sortKey="Tessonnier, T" sort="Tessonnier, T" uniqKey="Tessonnier T" first="T" last="Tessonnier">T. Tessonnier</name><affiliation wicri:level="3"><nlm:affiliation>Centre François Baclesse, 3 Avenue du Général Harris, 14000 Caen, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Centre François Baclesse, 3 Avenue du Général Harris, 14000 Caen</wicri:regionArea><placeName><region type="region" nuts="2">Région Normandie</region><region type="old region" nuts="2">Basse-Normandie</region><settlement type="city">Caen</settlement></placeName></affiliation></author><author><name sortKey="Toufique, Y" sort="Toufique, Y" uniqKey="Toufique Y" first="Y" last="Toufique">Y. Toufique</name><affiliation wicri:level="1"><nlm:affiliation>Texas A&M University at Qatar, 23874 Doha, Qatar; Institut Superieur des Sciences de la Santé de Settat, Morocco.</nlm:affiliation><country xml:lang="fr">Maroc</country><wicri:regionArea>Texas A&M University at Qatar, 23874 Doha, Qatar; Institut Superieur des Sciences de la Santé de Settat</wicri:regionArea><wicri:noRegion>Qatar; Institut Superieur des Sciences de la Santé de Settat</wicri:noRegion></affiliation></author><author><name sortKey="Vlachoudis, V" sort="Vlachoudis, V" uniqKey="Vlachoudis V" first="V" last="Vlachoudis">V. Vlachoudis</name><affiliation wicri:level="1"><nlm:affiliation>CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>CERN - European Organization for Nuclear Research, CH-1211 Genève 23</wicri:regionArea><wicri:noRegion>CH-1211 Genève 23</wicri:noRegion></affiliation></author><author><name sortKey="Parodi, K" sort="Parodi, K" uniqKey="Parodi K" first="K" last="Parodi">K. Parodi</name><affiliation wicri:level="4"><nlm:affiliation>Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Ludwig-Maximilians-Universität München, Am Coulombwall 1, 85748 Garching</wicri:regionArea><placeName><region type="land" nuts="1">Bavière</region><region type="district" nuts="2">District de Haute-Bavière</region><settlement type="city">Garching bei München</settlement></placeName><orgName type="university">Université Louis-et-Maximilien de Munich</orgName></affiliation></author><author><name sortKey="Ferrari, A" sort="Ferrari, A" uniqKey="Ferrari A" first="A" last="Ferrari">A. Ferrari</name><affiliation wicri:level="1"><nlm:affiliation>CERN - European Organization for Nuclear Research, CH-1211 Genève 23, Switzerland.</nlm:affiliation><country xml:lang="fr">Suisse</country><wicri:regionArea>CERN - European Organization for Nuclear Research, CH-1211 Genève 23</wicri:regionArea><wicri:noRegion>CH-1211 Genève 23</wicri:noRegion></affiliation></author></analytic><series><title level="j">Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)</title><idno type="eISSN">1724-191X</idno><imprint><date when="2018" type="published">2018</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Image Processing, Computer-Assisted (MeSH)</term><term>Monte Carlo Method (MeSH)</term><term>Positron-Emission Tomography (methods)</term><term>Signal-To-Noise Ratio (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Méthode de Monte Carlo (MeSH)</term><term>Rapport signal-bruit (MeSH)</term><term>Tomographie par émission de positons (méthodes)</term><term>Traitement d'image par ordinateur (MeSH)</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Positron-Emission Tomography</term></keywords><keywords scheme="MESH" qualifier="méthodes" xml:lang="fr"><term>Tomographie par émission de positons</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Image Processing, Computer-Assisted</term><term>Monte Carlo Method</term><term>Signal-To-Noise Ratio</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Méthode de Monte Carlo</term><term>Rapport signal-bruit</term><term>Traitement d'image par ordinateur</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The new developments of the FLUKA Positron-Emission-Tomography (PET) tools are detailed. FLUKA is a fully integrated Monte Carlo (MC) particle transport code, used for an extended range of applications, including Medical Physics. Recently, it provided the medical community with dedicated simulation tools for clinical applications, including the PET simulation package. PET is a well-established imaging technique in nuclear medicine, and a promising method for clinical in vivo treatment verification in hadrontherapy. The application of clinically established PET scanners to new irradiation environments such as hadrontherapy requires further experimental and theoretical research to which MC simulations could be applied. The FLUKA PET tools, besides featuring PET scanner models in its library, allow the configuration of new PET prototypes via the FLUKA Graphical User Interface (GUI) Flair. Both the beam time structure and scan time can be specified by the user, reproducing PET acquisitions in time, in a particle therapy scenario. Furthermore, different scoring routines allow the analysis of single and coincident events, and identification of parent isotopes generating annihilation events. Two reconstruction codes are currently supported: the Filtered Back-Projection (FBP) and Maximum-Likelihood Expectation Maximization (MLEM), the latter embedded in the tools. Compatibility with other reconstruction frameworks is also possible. The FLUKA PET tools package has been successfully tested for different detectors and scenarios, including conventional functional PET applications and in beam PET, either using radioactive sources, or simulating hadron beam irradiations. The results obtained so far confirm the FLUKA PET tools suitability to perform PET simulations in R&D environment.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Autriche</li><li>Espagne</li><li>France</li><li>Maroc</li><li>Qatar</li><li>Suisse</li></country><region><li>Basse-Normandie</li><li>Bavière</li><li>Canton de Genève</li><li>Castille-et-León</li><li>District de Haute-Bavière</li><li>Région Normandie</li><li>Vienne (Autriche)</li></region><settlement><li>Caen</li><li>Garching bei München</li><li>Genève</li><li>Vienne (Autriche)</li></settlement><orgName><li>Université Louis-et-Maximilien de Munich</li><li>Université de Genève</li></orgName></list><tree><country name="Allemagne"><region name="Bavière"><name sortKey="Augusto, R S" sort="Augusto, R S" uniqKey="Augusto R" first="R S" last="Augusto">R S Augusto</name></region><name sortKey="Bauer, J" sort="Bauer, J" uniqKey="Bauer J" first="J" last="Bauer">J. Bauer</name><name sortKey="Gianoli, C" sort="Gianoli, C" uniqKey="Gianoli C" first="C" last="Gianoli">C. Gianoli</name><name sortKey="Parodi, K" sort="Parodi, K" uniqKey="Parodi K" first="K" last="Parodi">K. Parodi</name></country><country name="Qatar"><noRegion><name sortKey="Bouhali, O" sort="Bouhali, O" uniqKey="Bouhali O" first="O" last="Bouhali">O. Bouhali</name></noRegion></country><country name="Suisse"><region name="Canton de Genève"><name sortKey="Cuccagna, C" sort="Cuccagna, C" uniqKey="Cuccagna C" first="C" last="Cuccagna">C. Cuccagna</name></region><name sortKey="Ferrari, A" sort="Ferrari, A" uniqKey="Ferrari A" first="A" last="Ferrari">A. Ferrari</name><name sortKey="Vlachoudis, V" sort="Vlachoudis, V" uniqKey="Vlachoudis V" first="V" last="Vlachoudis">V. Vlachoudis</name></country><country name="Autriche"><region name="Vienne (Autriche)"><name sortKey="Kozlowska, W S" sort="Kozlowska, W S" uniqKey="Kozlowska W" first="W S" last="Kozłowska">W S Kozłowska</name></region></country><country name="Espagne"><region name="Castille-et-León"><name sortKey="Ortega, P G" sort="Ortega, P G" uniqKey="Ortega P" first="P G" last="Ortega">P G Ortega</name></region></country><country name="France"><region name="Région Normandie"><name sortKey="Tessonnier, T" sort="Tessonnier, T" uniqKey="Tessonnier T" first="T" last="Tessonnier">T. Tessonnier</name></region></country><country name="Maroc"><noRegion><name sortKey="Toufique, Y" sort="Toufique, Y" uniqKey="Toufique Y" first="Y" last="Toufique">Y. Toufique</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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|wiki= Wicri/Sante
|area= MaghrebDataLibMedV2
|flux= Main
|étape= Exploration
|type= RBID
|clé= pubmed:30017561
|texte= An overview of recent developments in FLUKA PET tools.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:30017561" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a MaghrebDataLibMedV2
| This area was generated with Dilib version V0.6.38. |  |